Computational Neuropathology Lab

University of Wisconsin–Madison

We develop artificial intelligence and machine-learning methods for computational neuropathology. Our research integrates digital histopathology, whole-slide imaging, spatial transcriptomics, and multimodal data to improve disease quantification, biomarker discovery, and understanding of Alzheimer’s disease and related neurodegenerative disorders.

Research areas

Open science

We share models, datasets, and open-source tools that support transparent, reproducible biomedical research. Please consult each repository for documentation, licensing, intended use, and limitations.

Principal investigator

Jeffrey Nirschl, MD, PhD Physician-scientist and neuropathologist Assistant Professor of Pathology, University of Wisconsin–Madison